Autosomal aberrations

2n + 1 → Trisomy, 2n − 1 → Monosomy.

Cri-du-chat Syndrome (5p−) – deletion on short arm of chromosome 5.
🧬 (2021) “Chromosomal aberrations can play havoc with the human body and mind.” Explain.

Risk increases with maternal age.

Mosaic Down Syndrome – some cells 47,+21; others normal 46.
Turner mosaic – some cells 45,X; others 46,XX.
🧬 (2021) “Chromosomal aberrations can play havoc with the human body and mind.” Explain.
Chromosomal aberrations disturb the normal gene dosage and gene regulation, thereby affecting multiple organ systems simultaneously. Because many genes are involved, their impact on the human body and mind can be profound.

Micrognathia (small jaw), clenched fists with overlapping fingers.

PTC Tasting: The ability to taste the bitter chemical Phenylthiocarbamide is a dominant trait (TT, Tt).

A study of a local tribe that ignores the impact of global capitalism or state-led industrialization (such as the mining in the DRC or phosphate excavation on Banaba Island) fails to capture the true reality of that culture’s survival.

Bronislaw Malinowski | Fieldwork; Cultural Anthropology
Franz Boas | Cultural Anthropology; Historical Particularism
Benjamin Lee Whorf | Linguistic Relativity
Individual as Active Agent: Scholars like Alexander Goldenweiser and Edward Sapir argued that culture is not an abstract force independent of humans. By assuming a closed system, anthropologists overlook individual biographies and the "personal particularity" that creative individuals inject into the cultural stream to drive innovation.