Q66 · UPSC Prelims 2021 · Set A · Current Affairs and GK

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In the context of hereditary diseases, consider the following statements:1.Passing on mitochondrial diseases from parent to child can be prevented by mitochondrial replacement therapy either before or after in vitro fertilization of egg.2.A child inherits mitochondrial diseases

A 1 only
B 2 only
C Both 1 and 2
D Neither 1 nor 2

Correct answer: (c) Both 1 and 2

Explanation

  1. A

    1 only

    1 only. Maternal inheritance of mitochondria is also true.

  2. B

    2 only

    2 only. Mitochondrial replacement can be done around IVF.

  3. C

    Both 1 and 2

    Both. MRT can be used with IVF; a child inherits mitochondrial DNA from the mother.

  4. D

    Neither 1 nor 2

    Neither. Both hold.

Summary. Official key is (c) both. Mitochondrial disease is transmitted through the egg. Replacement therapy (three-person IVF and related methods) can be applied in the IVF window to break that line.

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